A Practical Guide to Human Cancer Genetics

A Practical Guide to Human Cancer Genetics

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This is a comprehensive and up-to-date guide to the diagnosis, clinical features and management of inherited disorders conferring cancer susceptibility. It is fully updated with much molecular, screening and management information. It covers risk analysis and genetic counselling for individuals with a family history of cancer. It also discusses predictive testing and the organisation of the cancer genetics service. There is information about the genes causing Mendelian cancer predisposing conditions and their mechanism of action. It aims to provide such details in a practical format for geneticists and clinicians in all disciplines.1999) Turcot syndrome (HNPCC) (Tamiya et al. 2000; Chan et al. 1999; Taylor et al. 1999; Leung et al. 1998; Van Meir 1998; Buerstedde et al. 1995; Hamilton et al. 1995) MLH1, MSH2, PMS1, PMS2 Hereditary retinoblastoma (Elias et al.

Title:A Practical Guide to Human Cancer Genetics
Author: Shirley V. Hodgson, William D. Foulkes, Charis Eng, Eamonn Maher
Publisher:Springer Science & Business Media - 2013-11-22

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